发明名称 A PEG-ALBUMIN COMPOSITION HAVING AT LEAST ONE PROTECTED THIOL REGION AS A PLATFORM FOR MEDICATIONS
摘要 This composition comprises a polyethylene glycol-albumin composition having at least one protected thiol region wherein the composition comprises PEG-AlbCys34 with Cys-34 preserved as a thiol. The albumin is linked to medications such as, antioxidants with a reduced sulfhydryl group through the Cys 34 residing on the albumin. The compositions are useful in treating patients.
申请公布号 EP2413694(A1) 申请公布日期 2012.02.08
申请号 EP20100759156 申请日期 2010.04.02
申请人 THE UNIVERSITY OF TOLEDO 发明人 ASSALY, RAGHEB;DIGMAN, JOHN, DAVID;SHAPIRO, JOSEPH, I.
分类号 A01N37/18;A61K38/00 主分类号 A01N37/18
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