发明名称 |
GENOMIC EDITING OF GENES INVOLVED WITH PARKINSONS DISEASE |
摘要 |
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with Parkinson's disease. In particular, the animals or cells are generated using a zinc finger nuclease-mediated editing process. Also provided are methods of assessing the effects of agents in genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with Parkinson's disease. |
申请公布号 |
US2012030778(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
US201113191901 |
申请日期 |
2011.07.27 |
申请人 |
WEINSTEIN EDWARD;SIMMONS PHIL;SIGMA-ALDRICH CO., LLC. |
发明人 |
WEINSTEIN EDWARD;SIMMONS PHIL |
分类号 |
A61B5/00;A01K67/027;A61K49/00;C12N5/10 |
主分类号 |
A61B5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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