| 发明名称 |
Monoclonal antibodies against claudin-18 for treatment of cancer |
| 摘要 |
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDl 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder. |
| 申请公布号 |
AU2006316767(B2) |
申请公布日期 |
2012.02.02 |
| 申请号 |
AU20060316767 |
申请日期 |
2006.11.24 |
| 申请人 |
JOHANNES GUTENBERG-UNIVERSITAT MAINZ, VERTRETEN DURCH DEN PRASIDENTEN;GANYMED PHARMACEUTICALS AG |
发明人 |
FRITZ, STEFAN;USENER, DIRK;BRANDENBURG, GUNDA;SCHRODER, ANJA KRISTINA;THIEL, PHILIPPE;GEPPERT, HARALD-GERHARD;UHEREK, CRISTOPH;TURECI, OZLEM;SAHIN, UGUR |
| 分类号 |
C07K16/30;A61K39/395;A61K47/48;A61P35/00;C12N5/12 |
主分类号 |
C07K16/30 |
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