发明名称 New receptor agonist having renin-suppressing activity, antihypertrophic activity and influence of second messenger cyclic guanosine monophosphate during vasodilation, natriuresis and diuresis, useful to treat e.g. nephrotic syndrome
摘要 <p>Receptor agonist having renin-suppressing activity, antihypertrophic (antifibrotic) activity and influence of second messenger cyclic guanosine monophosphate (cGMP) during vasodilation, natriuresis and diuresis, is new. An independent claim is included for a nucleic acid sequence encoding the receptor agonists. ACTIVITY : Cardiovascular-Gen.; Cardiant; Vasotropic; Nephrotropic; Hypotensive; Antiinflammatory; Hepatotropic; Respiratory-Gen. MECHANISM OF ACTION : Natriuretic peptide receptor A agonist; Natriuretic peptide receptor B agonist.</p>
申请公布号 DE102010032482(A1) 申请公布日期 2012.02.02
申请号 DE20101032482 申请日期 2010.07.28
申请人 JUSTUS-LIEBIG-UNIVERSITAET GIESEN 发明人 WALTHER, THOMAS, PROF.DR.
分类号 A61K45/00;A61K38/00;A61P1/16;A61P9/00;A61P15/10 主分类号 A61K45/00
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