发明名称 |
New receptor agonist having renin-suppressing activity, antihypertrophic activity and influence of second messenger cyclic guanosine monophosphate during vasodilation, natriuresis and diuresis, useful to treat e.g. nephrotic syndrome |
摘要 |
<p>Receptor agonist having renin-suppressing activity, antihypertrophic (antifibrotic) activity and influence of second messenger cyclic guanosine monophosphate (cGMP) during vasodilation, natriuresis and diuresis, is new. An independent claim is included for a nucleic acid sequence encoding the receptor agonists. ACTIVITY : Cardiovascular-Gen.; Cardiant; Vasotropic; Nephrotropic; Hypotensive; Antiinflammatory; Hepatotropic; Respiratory-Gen. MECHANISM OF ACTION : Natriuretic peptide receptor A agonist; Natriuretic peptide receptor B agonist.</p> |
申请公布号 |
DE102010032482(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
DE20101032482 |
申请日期 |
2010.07.28 |
申请人 |
JUSTUS-LIEBIG-UNIVERSITAET GIESEN |
发明人 |
WALTHER, THOMAS, PROF.DR. |
分类号 |
A61K45/00;A61K38/00;A61P1/16;A61P9/00;A61P15/10 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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