发明名称 DELIVERY OF ANTIPSYCHOTICS THROUGH AN INHALATION ROUTE
摘要 The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of an antipsychotic. In a method aspect of the present invention, an antipsychotic is delivered to a mammal through an inhalation route. The method comprises: a) Heating a composition, wherein the compositi on comprises at least 5 percent by weight of an antipsychotic, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering an antipsychotic through an inhalati on route to a mammal is provided which comprises: a) a composition comprising a t least 5 percent by weight of an antipsychotic; and, b) a device that forms a n antipsychotic containing aerosol from the composition, for inhalation by the mammal.
申请公布号 CA2446917(A1) 申请公布日期 2002.11.28
申请号 CA20022446917 申请日期 2002.05.20
申请人 ALEXZA MOLECULAR DELIVERY CORPORATION 发明人 RABINOWITZ, JOSHUA D.;ZAFFARONI, ALEJANDRO C.
分类号 A61K9/12;A61K9/00;A61K9/72;A61K31/00;A61K31/13;A61K31/137;A61K31/138;A61K31/165;A61K31/167;A61K31/19;A61K31/192;A61K31/216;A61K31/27;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/405;A61K31/407;A61K31/4196;A61K31/421;A61K31/422;A61K31/423;A61K31/437;A61K31/439;A61K31/4402;A61K31/4418;A61K31/4525;A61K31/4545;A61K31/46;A61K31/473;A61K31/48;A61K31/485;A61K31/49;A61K31/495;A61K31/496;A61K31/4985;A61K31/501;A61K31/505;A61K31/519;A61K31/53;A61K31/5415;A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61K45/00;A61K47/48;A61M11/00;A61P15/10;A61P21/02;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/32;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07D471/04;C07D487/04;F24J1/00;(IPC1-7):A61K9/72 主分类号 A61K9/12
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