METHOD FOR PURIFYING ACTIVE POLYPEPTIDES OR IMMUNOCOJUGATES
摘要
The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography.
申请公布号
WO2012015912(A1)
申请公布日期
2012.02.02
申请号
WO2011US45524
申请日期
2011.07.27
申请人
MEDIMMUNE, LLC;LINKE, THOMAS;WANG, WILLIAM, K.;SHAH, AMBARISH;SATHISH, HASIGE;HUNTER, ALAN;THOMPSON, CHRISTOPHER
发明人
LINKE, THOMAS;WANG, WILLIAM, K.;SHAH, AMBARISH;SATHISH, HASIGE;HUNTER, ALAN;THOMPSON, CHRISTOPHER
