| 发明名称 |
Compositions and methods for regulation of tumor necrosis factor-alpha |
| 摘要 |
<p>The present disclosure relates to compositions and methods relating to an interleukin-18-inducible cytokine termed tumor necrosis factor-alpha inducing factor (TAIF) or interleukin-32 (IL-32). In particular, the present disclosure provides compositions and methods for treating autoimmune diseases and cancer, in part by regulation of tumor necrosis factor-alpha expression.</p> |
| 申请公布号 |
EP2357238(A3) |
申请公布日期 |
2012.02.01 |
| 申请号 |
EP20110154031 |
申请日期 |
2004.11.12 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
KIM, SOO-HYUN;DINARELLO, CHARLES A;AZAM, TANIA |
| 分类号 |
C12N15/24;A61K38/00;A61K39/395;C07K14/54;C07K16/24;C07K19/00;C12N;C12N1/15;C12N1/19;C12N5/10 |
主分类号 |
C12N15/24 |
| 代理机构 |
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代理人 |
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