发明名称 |
COMBINATION DRUG CONTAINING PROBUCOL AND A TETRAZOLYLALKOXY-DIHYDROCARBOSTYRIL DERIVATIVE WITH SUPEROXIDE SUPRESSANT EFFECTS |
摘要 |
<p>This invention relates to a combination drug comprising a combination of a tetrazolylalkoxy-dihydrocarbostyril derivative of the formula:
wherein R is cycloalkyl, A is lower alkylene, and the bond between 3-and 4-positions of carbostyril nucleus is single bond or double bond, or a salt thereof and Probucol, which is useful for preventing and treating cerebral infarction including acute cerebral infarction and chronic cerebral infarction, arteriosclerosis, renal diseases (e.g. diabetic nephropathy, renal failure, nephritis), and diabetes owing to synergistic superoxide suppressant effects of the combination.</p> |
申请公布号 |
EP1942895(B1) |
申请公布日期 |
2012.02.01 |
申请号 |
EP20060810355 |
申请日期 |
2006.09.14 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
HONG, KI, WHAN;YOSHIKAWA, TOMOHIRO |
分类号 |
A61K31/4704;A61K31/095;A61P3/00;A61P7/00;A61P9/00 |
主分类号 |
A61K31/4704 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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