| 发明名称 |
INHIBITORS OF HISTONE DEACETYLASE |
| 摘要 |
The invention relates to the inhibition of histone deacetylase. The invention provides compounds for inhibiting histone deacetylase enzymatic activity. The compounds for inhibiting histone deacetylase enzymatic activity can be represented by the formulas Cy-L1-Ar Y1-C(O)-NH-Z Cy-L2 Ar-Y2-C(O)NH-Z Cy-L3 Ar-Y3-C(O)NH-Z, wherein Cy, L1, L2, L3, Ar, Y1, Y2, Y3 and Z are as defined in the application.
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| 申请公布号 |
CA2391952(C) |
申请公布日期 |
2012.01.31 |
| 申请号 |
CA20002391952 |
申请日期 |
2000.11.22 |
| 申请人 |
METHYLGENE INC. |
发明人 |
DELORME, DANIEL;RUEL, REJEAN;LAVOIE, RICO;THIBAULT, CARL;ABOU-KHALIL, ELIE |
| 分类号 |
C07C311/21;C12N9/99;A61K31/16;A61K31/165;A61K31/166;A61K31/17;A61K31/18;A61K31/341;A61K31/343;A61K31/38;A61K31/381;A61K31/41;A61K31/433;A61K31/44;A61K31/4402;A61K31/4406;A61K31/47;A61K31/711;A61K48/00;A61P35/00;A61P43/00;C07C259/06;C07C259/10;C07C275/42;C07C311/13;C07C311/29;C07C311/44;C07C317/44;C07C321/28;C07D213/71;C07D213/76;C07D215/36;C07D285/12;C07D285/135;C07D307/46;C07D307/54;C07D307/68;C07D307/91;C07D333/34;C07D333/38;C07D333/62 |
主分类号 |
C07C311/21 |
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