发明名称 |
ABC transporter ligand GATX1 |
摘要 |
Compositions and methods of using scorpion venom peptide that is a ligand for ABC transporters. One aspect provides a peptide having at least 80% sequence identity to SEQ ID NO: 1. The peptide Is believed to have a molecular mass of about 3.7 kDa and specifically interacts with cystic fibrosis transmembrane conductance regulator. Methods of treating a disorder or symptom of a disorder related to aberrant ABC transporter activity are also provided.
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申请公布号 |
US8106013(B2) |
申请公布日期 |
2012.01.31 |
申请号 |
US20070299881 |
申请日期 |
2007.05.18 |
申请人 |
MCCARTY NAEL;FULLER MATTHEW;KUBANEK JULIA;GEORGIA TECH RESEARCH CORPORATION |
发明人 |
MCCARTY NAEL;FULLER MATTHEW;KUBANEK JULIA |
分类号 |
A61K38/16;A61P1/12;A61P13/12;C07K14/435 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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