| 摘要 |
Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: A represents a group selected from one of the following: (CH2)t—, —(CH2)—S(O)z—, or —S(O)z—(CH2)—, B is a heteroaryl, optionally substituted; R is a group selected from the following: alkyl, aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; R′ is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R″, a ketonic group of formula —C(O)—Z′, wherein Z′ is as defined below; a substituent having an hydroxyl function of formula —CH(OH)—Z′; an amide substituent of formula —C(O)—NH-T′. |
