| 发明名称 |
Mylks as modifiers of branching morphogenesis and methods of use |
| 摘要 |
Human MYLK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MYLK are provided. |
| 申请公布号 |
US8105785(B2) |
申请公布日期 |
2012.01.31 |
| 申请号 |
US20040556637 |
申请日期 |
2004.06.18 |
| 申请人 |
PLOWMAN GREGORY D.;KARIM FELIX D.;SWIMMER CANDACE;HABECK HINRICH ALEXANDER;KOBLIZEK THOMAS I.;SCHULTE-MERKER STEFAN;EISENMANN ULRIKE;STOTT GORDON MARK;TROWE TORSTEN;VOGEL ANDREAS MICHAEL;ODENTHAL JOERG HEINRICH;SCHEEL JOCHEN KONRAD;WILL TORSTEN TILMANN;JIN YINSHENG;BJERKE LYNN MARGARET;HEUER TIMOTHY S.;EXELIXIS, INC. |
发明人 |
PLOWMAN GREGORY D.;KARIM FELIX D.;SWIMMER CANDACE;HABECK HINRICH ALEXANDER;KOBLIZEK THOMAS I.;SCHULTE-MERKER STEFAN;EISENMANN ULRIKE;STOTT GORDON MARK;TROWE TORSTEN;VOGEL ANDREAS MICHAEL;ODENTHAL JOERG HEINRICH;SCHEEL JOCHEN KONRAD;WILL TORSTEN TILMANN;JIN YINSHENG;BJERKE LYNN MARGARET;HEUER TIMOTHY S. |
| 分类号 |
C12Q1/68;C07K14/47;C12N;C12Q;G01N33/50;G01N33/53 |
主分类号 |
C12Q1/68 |
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