发明名称 |
Plant production of immunoglobulins with reduced fucosylation |
摘要 |
This invention provides for the plant production of immunoglobulins, wherein at least a portion of the glycans attached to the immunoglobulins lack fucose. The invention also provides the constructs; plasmids; vectors; transformed plant cells, transformed plant calli; transformed plant tissues (e.g., leaves, seeds, tubers, etc.); transformed whole plants used to produce such immunoglobulins; methods of producing the immunoglobulins; the immunoglobulins produced by the disclosed methods; and the use of such immunoglobulins. |
申请公布号 |
US8106169(B2) |
申请公布日期 |
2012.01.31 |
申请号 |
US20030536875 |
申请日期 |
2003.11.28 |
申请人 |
BRIGGS KRISTEN;GLANCY TODD;HEIN MICH B.;HIATT ANDREW C.;KARNOUP ANTON S.;ANDERSON W. H. KERR;PAREDDY DAYAKAR;PETOLINO JOSEPH;RUBIN-WILSON BETH;TAYLOR DOUG;ROBERTS JEAN L.;PHYTON HOLDINGS, LLC |
发明人 |
BRIGGS KRISTEN;GLANCY TODD;HEIN MICH B.;HIATT ANDREW C.;KARNOUP ANTON S.;ANDERSON W. H. KERR;PAREDDY DAYAKAR;PETOLINO JOSEPH;RUBIN-WILSON BETH;TAYLOR DOUG;ROBERTS JEAN L. |
分类号 |
C07K16/08;C07K16/00;C07K16/28;C12N15/82 |
主分类号 |
C07K16/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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