发明名称 BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR.
摘要 <p>The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I' and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. Formula (I) (I') wherein n is 1 or 2; R1 is hydrogen or methyl and is positioned vicinal to the radical R1; R2 is hydrogen or methyl; R3 is C1-C3 alkyl; R4 is hydrogen, C1-C4 alkyl, cyclopropyl, C3-C4 cycloalkylmethyl or fluorinated C1-C4 alkyl; R5 is hydrogen, fluorine, chlorine, C1-C4 alkyl, fluorinated C1-C4 alkyl, C1-C4 alkoxy or fluorinated C1-C4 alkoxy; and R6 is hydrogen, fluorine or chlorine.</p>
申请公布号 MX2011011519(A) 申请公布日期 2012.01.30
申请号 MX20110011519 申请日期 2010.04.29
申请人 ABBOTT GMBH & CO. KG. 发明人 LILIANE UNGER;KARLA DRESCHER;ANDREAS HAUPT;GISELA BACKFISCH;MIN ZHANG;KARSTEN WICKE;ANTON BESPALOV;BARBARA VOGG;FRAUKE POHLKI;ANA-LUCIA RELO;JUERGEN DELZER
分类号 C07D243/08;A61K31/495;A61K31/496;A61P3/04;A61P25/00;C07D295/135;C07D405/12 主分类号 C07D243/08
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