发明名称 TETOMILAST POLYMORPHS
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: present inventions refers to a new crystalline form of tetomilast hydrate of the X-ray powder diffraction spectrum having characteristic peaks at the angle 20=10.6, 12.9, 21.1, 22.3 and 25.0, to a new crystalline form of anhydrous tetomilast type C of the X-ray powder diffraction spectrum having characteristic peaks at the angle 2=4.2, 8.2, 12.0, 16.4, 24.7 and 25.9, to a new crystalline form of acetonitrile tetomilast solvate of the X-ray powder diffraction spectrum having characteristic peaks at the angle 2=3.6, 7.1, 10.6, 14.2 and 24.8, to based pharmaceutical compositions and to methods for preparing. ^ EFFECT: new crystalline forms shows useful processing characteristics with relation to preparing pharmaceutical drugs of them. ^ 13 cl, 14 dwg, 8 ex
申请公布号 RU2441002(C2) 申请公布日期 2012.01.27
申请号 RU20090147223 申请日期 2007.03.15
申请人 OTSUKA FARMAS'JUTIKAL KO., LTD. 发明人 AOKI SATOSI;NAKAJA KENDZI;SOTA MASAKHIRO;ISIGAMI MASASI
分类号 A61K31/425;A61K31/427;A61K31/4436;A61K31/4439;A61P1/00;A61P3/00;A61P9/10;A61P11/00;A61P17/00;A61P19/00;A61P25/00;C07D417/04 主分类号 A61K31/425
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