The invention relates to a method for the production of L-carnitine, wherein a chiral ß-lactone carnitine precursor is obtained by a [2+2] cycloaddition of ketene with an aldehyde X-CH2-CHO, wherein X is selected from CI, Br, I and trimethylamine, in the presence of a chiral catalyst.
申请公布号
WO2012010296(A1)
申请公布日期
2012.01.26
申请号
WO2011EP03620
申请日期
2011.07.20
申请人
LONZA LTD;HANSELMANN, PAUL;KLEGRAF, ELLEN;ELZNER, STEFAN;QUITTMANN, WILHELM;FISCHER, DANIEL FRIEDRICH
发明人
HANSELMANN, PAUL;KLEGRAF, ELLEN;ELZNER, STEFAN;QUITTMANN, WILHELM;FISCHER, DANIEL FRIEDRICH