发明名称 A COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT
摘要 The present invention relates to complexes of a) bi-specific antibodies and antibody fragments against a target protein and b) a digoxigenin conjugated to a therapeutic or diagnostic agent, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof.
申请公布号 WO2011003557(A8) 申请公布日期 2012.01.26
申请号 WO2010EP04051 申请日期 2010.07.05
申请人 F. HOFFMANN-LA ROCHE AG;BRINKMANN, ULRICH;CROASDALE, REBECCA;LAU, WILMA;GEORGES, GUY;HAAS, ALEXANDER;HOFFMANN, EIKE;METZ, SILKE;MUNDIGL, OLAF;SCHEUER, WERNER;STRACKE, JAN OLAF 发明人 BRINKMANN, ULRICH;CROASDALE, REBECCA;LAU, WILMA;GEORGES, GUY;HAAS, ALEXANDER;HOFFMANN, EIKE;METZ, SILKE;MUNDIGL, OLAF;SCHEUER, WERNER;STRACKE, JAN OLAF
分类号 A61K39/395;A61K47/48;C07K16/16;C07K16/28;C07K16/32;C07K16/44;C07K16/46;C12N15/113 主分类号 A61K39/395
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