COMPLEX MIRNA SETS AS NOVEL BIOMARKERS FOR GASTRIC CANCER

摘要

The present invention relates to single polynucleotides or sets of polynucleotides for detecting single miRNAs or sets of miRNAs for diagnosing and/or prognosing of gastric cancer in a blood sample such as blood cell sample from a human patient. Further, the present invention relates to means for diagnosing and/or prognosing of gastric cancer comprising said polynucleotides or sets of polynucleotides. Furthermore, the present invention relates to a method for diagnosing and/or prognosing of gastric cancer based on the determination of expression profiles of single miRNAs or sets of miRNAs representative for gastric cancer. In addition, the present invention relates to a kit for diagnosing and/or prognosing of gastric cancer comprising means for determining expression profiles of single miRNAs or sets of miRNAs representative for gastric cancer and optionally at least one reference and/or algorithm or mathematical function comprised on at least one data carrier.