| 发明名称 |
HSP90 INHIBITORS WITH MODIFIED TOXICITY |
| 摘要 |
The invention provides purified 19-substituted geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of symptoms of cancer and other proliferative tissue disorders. |
| 申请公布号 |
US2012022011(A1) |
申请公布日期 |
2012.01.26 |
| 申请号 |
US20080673996 |
申请日期 |
2008.08.22 |
| 申请人 |
ROSS DAVID;SIEGEL DAVID;GUO WENCHANG;MOODY CHRISTOPHER J.;MCERLEAN CHRISTOPHER S.P.;THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
ROSS DAVID;SIEGEL DAVID;GUO WENCHANG;MOODY CHRISTOPHER J.;MCERLEAN CHRISTOPHER S.P. |
| 分类号 |
A61K31/704;A61K31/337;A61K31/395;A61P35/00;C07D225/06 |
主分类号 |
A61K31/704 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
