发明名称 3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL]OCTANE- OR HEPTANE-NITRILE AS JAK INHIBITORS.
摘要 The present invention relates to the Janus kinase (JAK) inhibitors 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)-1H-pyrazol-l-yl]octanenitrile or 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-y1)-1H- pyrazol-l-yl]heptanenitrile, as well as its compositions and methods of use, which is useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, skin disorders, cancer, and other diseases.
申请公布号 MX2011012262(A) 申请公布日期 2012.01.25
申请号 MX20110012262 申请日期 2010.05.21
申请人 INCYTE CORPORATION 发明人 JAMES D. RODGERS;YUN-LONG LI
分类号 A61K31/519;A61P17/00;A61P27/02;A61P29/00;A61P35/00;C07D487/04 主分类号 A61K31/519
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