METHOD FOR PREPARING WATER-SOLUBLE CHITOSAN PARA-AMINOSALICYLATE

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, namely to phthisiology and pharmaceutical industry. A method for preparing a water-soluble chitosan para-aminosalicylate consists in preparing an aqueous solution of para-aminosalicylic acid (2.8 wt %) at temperature 90C, adding low-molecular chitosan (low molecular weight 3.9 and 30 kDa) in amount 2.8 wt % in mixing with a mechanical mixer, dispersing a reaction mixture at temperature 85C for 40 minutes. After termination of the process, the reaction mixture is vacuumised; a solid residue is dried in vacuum at temperature 30C. ^ EFFECT: preparation of medicines for tuberculosis. ^ 3 ex, 9 dwg