PYRAZOLE COMPOUND

摘要

The present invention relates to a novel serotonin reuptake inhibitor having 5-HT2C antagonism, particularly, also having 5-HT2C inverse agonism, which contains a compound represented by formula (1) or a pharmaceutically acceptable salt thereof and has antidepressive activity and anxiolytic activity. In formula (1), R1, R2, R3, and R4 each independently represent a hydrogen atom, a C1-6 alkyl group, or the like; R5 represents a C4-7 alkyl group or -(CR8R9)r-E; R6, R7, R8, and R9 each independently represent a hydrogen atom, a fluorine atom, or a C1-6 alkyl group; A represents a C6-10 aryl group, a heteroaryl group, or the like; r represents 1, 2, 3, or 4; E represents a C3-8 cycloalkyl group, a C6-10 aryl group, or the like; L represents an oxygen atom, a sulfur atom, or -NR10-; n represents 1, 2, or 3; R10 represents a hydrogen atom, a C1-6 alkyl group, or the like; and X represents a hydrogen atom, a halogen atom, or the like.