This invention relates to anti-OX40L antibodies and, in particular, to anti-OX40L antibodies and variants thereof that contain a Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from inflammatory diseases.
申请公布号
AU2005284310(B2)
申请公布日期
2012.01.19
申请号
AU20050284310
申请日期
2005.09.16
申请人
F. HOFFMANN-LA ROCHE AG
发明人
SEEBER, STEFAN;PARREN, PAUL;FUENTES, MARIA;SCHUMACHER, RALF;REBERS, FRANK;GRAUS, YVO;VAN VUGT, MARTINE;ENDL, JOSEF;LABRIJN, ARAN;EUGUI, ELSIE;VAN DE WINKEL, JAN;LANZENDOERFER, MARTIN