LOW-PRESSURE ENVIRONMENT FOR FLUID TRANSFER DEVICES

摘要

The present application generally relates to devices for withdrawing a substance from the skin and/or from beneath the skin of a subject, and/or for delivering a substance to the skin and/or to a location beneath the skin of a subject. The devices comprise one or more skin insertion objects, such as needles or microneedles and one or more vacuum chambers having an internal pressure less than atmospheric pressure. The device is contained within an environment able to assist with maintenance of such pressures. For example, a package containing such an environment may also have a pressure less than atmospheric pressure, and/or the package may be molded to the device or otherwise have a shape that does not contain substantial gases that can "leak" into the device and alter the pressure of the vacuum chambers.