发明名称 |
Microorganisms with extended substrate utilization range |
摘要 |
The present invention relates to a microorganism of the genus Cupriavidus or Ralstonia, which is genetically modified to express phosphomannose isomerase (EC5.3.1.8) and facilitated diffusion protein for mannose uptake (EC1.3.1.74), and optionally mannofructokinase (EC2.7.1.4) and/or xylose isomerase (EC 5.3.1.5), xylulokinase (E 2.7.1.17) and xylose proton symporter E or a high affinity ABC- transporter. A modified Cupriavidus or Ralstonia host is capable of growing on mannose, xylose, arabinose, glucose, or galactose, or a combination thereof as the carbon source. |
申请公布号 |
EP2407531(A1) |
申请公布日期 |
2012.01.18 |
申请号 |
EP20100169808 |
申请日期 |
2010.07.16 |
申请人 |
NESTE OIL OYJ |
发明人 |
SICHWART, SHANNA;HASCHENHERMES, BIRGIT;BROEKER, DANIEL;STEINBUECHEL, ALEXANDER;HETZLER, STEFAN;KOSKINEN, PERTTU |
分类号 |
C12N1/20;C12N1/21;C12N1/22;C12N9/02;C12N9/12;C12N9/90;C12P7/62 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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