| 摘要 |
The invention relates to a binding compound, which binds the same epitope of human CD27 as monoclonal antibody hCD27.15, produced by hybridoma hCD27.15 which was deposited with the ATCC in on June 2, 2010 under number PTA-11008. In particular the invention relates to such binding compound of claim 1, comprising: an antibody heavy chain variable region comprising at least one CDR selected from the group consisting of SEQ ID NOs : 5, 6 and 7, or a variant of any of said sequences; and/or an antibody light chain variable region comprising at least one CDR selected from the group consisting of SEQ ID NOs: 8, 9 and 10, or a variant of any of said sequences. |
