发明名称 1, 2, 4-thiazolidin-3-one derivatives and their use in the treatment of cancer
摘要 According to the invention there is provided a compound of formula (I) wherein: A represents C(=N-W-D) or S; B represents S or C(-NH-W-D); when: A represents C(=N-W-D) and B represents S then the bond between B and the NH atom is a single bond; or A represents S and B represents C(-NH-W-D) then the bond between B and the NH atom is a double bond; X represents -Q-[CRR]-; W represents -[CRR]- or -C(O)-[CRR]-; Q represents a bond, -N(R)-, -S-, or -O-; A to A respectively represent C(R), C(R), C(R), C(R) and C(R), or, alternatively, up to two of A to A may independently represent N; D represents phenyl, pyridyl or pyrimidinyl optionally substituted by one or more R groups, which compounds are useful in the treatment of cancer.
申请公布号 AU2010270030(A1) 申请公布日期 2012.01.12
申请号 AU20100270030 申请日期 2010.07.08
申请人 BALTIC BIO AB 发明人 WESTMAN, JACOB;HALLETT, ALLAN;VAGBERG, JAN
分类号 C07D285/08;A61K31/433;C07D417/10;C07D417/12 主分类号 C07D285/08
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