发明名称 COMPOSITION AND METHOD OF DELIVERY OF PHARMACOLOGICAL AGENT
摘要 <P>PROBLEM TO BE SOLVED: To provide a method for reducing one or more side effects of administration of the pharmaceutical composition, the method for inhibiting microbial growth and oxidation in the pharmaceutical composition, and the method for enhancing transport and binding of a pharmaceutical agent to a cell, and to provide the pharmaceutical composition. <P>SOLUTION: There is provided the pharmaceutical composition including a pharmaceutical agent, such as paclitaxel, with human serum albumin in a specific ratio. There are provided the method of reducing the side effects associated with myelosuppression, neurotoxicity, hypersensitivity, inflammation, venous irritation, phlebitis, pain, skin irritation, and the method for enhancing transport of the pharmaceutical agent to the lesion in a human. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012006942(A) 申请公布日期 2012.01.12
申请号 JP20110167073 申请日期 2011.07.29
申请人 ABRAXIS BIOSCIENCE LLC 发明人 DESAI NEIL P;YANG ANDREW;CI SHERRY XIAOPEI;DE TAPAS;TRIEU VUONG;SOON-SHIONG PATRICK;BEALS GRIM BRIDGET;YAO QIANG
分类号 A61K38/00;A61K9/00;A61K9/107;A61K9/19;A61K31/00;A61K31/05;A61K31/337;A61K45/00;A61K47/18;A61K47/42;A61K47/48;A61P9/00;A61P19/02;A61P35/00;A61P43/00 主分类号 A61K38/00
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