发明名称 PROCESS FOR PREPARING MALATHION FOR PHARMACEUTICAL USE
摘要 The present invention provides a process for preparing a highly pure form of malathion having a reduced level of toxic impurities. In addition, the malathion prepared by the process of this invention is storage stable. The level of toxic impurities in the malathion, e.g., isomalathion, O,O,S-trimethyl phosphorodithioate (MeOOSPS), O,O,S-trimethyl phosphorothioate (MeOOSPO), O,S,S-trimethyl phosphorodithioate (MeOSSPO), malaoxon, isomalathion, diethyl fumarate, methyl malathion, dimethyl malathion, O,O-methyl,ethyl-S-(1,2-dicarboethoxy)ethyl-phosphorodithioate are lower than that of any other commercial preparation of malathion that may be used for pharmaceutical purposes.
申请公布号 US2012010175(A1) 申请公布日期 2012.01.12
申请号 US201113239750 申请日期 2011.09.22
申请人 TARO PHARMACEUTICALS NORTH AMERICA, INC. 发明人 GUTMAN DANIELLA;BAIDUSSI WAEL
分类号 A61K31/661;A61P33/14 主分类号 A61K31/661
代理机构 代理人
主权项
地址