发明名称 |
UTROPHIN PROMOTER ACTIVITY UPREGULATION FOR THE TREATMENT OF MUSCULAR DYSTROPHY |
摘要 |
Methods are provided for increasing utrophin promoter activity, utrophin expression or utrophin activity, and treating or reducing the symptoms of muscular dystrophy by administering to a subject in need thereof an effective amount of a composition comprising a utrophin promoter or activity upregulator. Muscular dystrophy includes but is not limited to Duchenne muscular dystrophy, Becker's muscular dystrophy, limb girdle muscular dystrophy, or a disease characterized by mutation or dysregulation of the dystrophin gene or an aberrant or dysfunctional dystrophin.
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申请公布号 |
US2012010176(A1) |
申请公布日期 |
2012.01.12 |
申请号 |
US200913129074 |
申请日期 |
2009.11.12 |
申请人 |
KHURANA TEJVIR S.;DIAMOND SCOTT L.;MOORWOOD CATHERINE;LOZYNSKA OLGA;NAPPER ANDREW D.;PISTILLI EMIDIO;SURI NEHA |
发明人 |
KHURANA TEJVIR S.;DIAMOND SCOTT L.;MOORWOOD CATHERINE;LOZYNSKA OLGA;NAPPER ANDREW D.;PISTILLI EMIDIO;SURI NEHA |
分类号 |
A61K31/352;A61K31/05;A61K31/12;A61K31/138;A61K31/351;A61K31/42;A61K31/427;A61K31/428;A61K31/4525;A61K31/565;A61K31/655;A61P21/00;C12N5/071 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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