发明名称 |
A PLANAR SUPPORT HAVING AN ULTRAFLAT SURFACE AND A DEVICE FOR DETECTING ANTIGENS COMPRISING SAID PLANAR SUPPORT |
摘要 |
A nanoarray or microarray of antibodies comprising a planar surface having an ultraflat surface is described, which is characterized in that it comprises a planar substrate functionalized with a first monolayer of linking molecules, preferably APTES molecules, and a second monolayer of small peptides of the general formula (I) capable of binding the Fc region of antibodies. The nanoarray or microarray of the invention comprises a plurality of capture antibodies immobilized on the planar support, preferably in the form of a matrix of spots, and is suitable to be used for detecting antigens in a biological sample by AFM imaging. Z-HN-R1-R2-R3-R4-R5-R6-NH-X-CO-G-COOH |
申请公布号 |
CA2804103(A1) |
申请公布日期 |
2012.01.12 |
申请号 |
CA20112804103 |
申请日期 |
2011.07.04 |
申请人 |
UNIVERSITA' DEGLI STUDI DI GENOVA |
发明人 |
FERRERA, FRANCESCA;IERARDI, VINCENZO;FILACI, GILBERTO;MILLO, ENRICO;DAMONTE, GIANLUCA;INDIVERI, FRANCESCO;VALBUSA, UGO |
分类号 |
G01N33/543;G01N33/552 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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