发明名称 |
Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects |
摘要 |
<p>The present invention provides compositions and methods for treating an osteochondral defect. In one embodiment, provided is a composition for treating an osteochondral defect comprising a biphasic biocompatible matrix and platelet derived growth factor (PDGF), wherein the biphasic biocompatible matrix comprises a scaffolding material and wherein the scaffolding material forms a porous structure comprising an osseous phase and a cartilage phase. In another embodiment, also provided is a method for treating an osteochondral defect in an individual comprising administering to the individual an effective amount of a composition comprising a biphasic biocompatible matrix and PDGF to at least one site of the osteochondral defect, wherein the biphasic biocompatible matrix comprises a scaffolding material and wherein the scaffolding material forms a porous structure comprising an osseous phase and a cartilage phase.</p> |
申请公布号 |
EP2403514(A1) |
申请公布日期 |
2012.01.11 |
申请号 |
EP20100749424 |
申请日期 |
2010.03.05 |
申请人 |
BIOMIMETIC THERAPEUTICS, INC. |
发明人 |
KESTLER, HANS, K.;NICKOLS, JOSHUA;WISNER-LYNCH, LESLIE, A.;LIU, YANCHUN;RODEN, COLLEEN, M. |
分类号 |
A61K38/18;A61L27/22;A61L27/54;A61L27/56 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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