发明名称 Substituted pyrazolo [1,5-a] pyrimidines as metabotropic glutamate antagonists
摘要 The present invention relates to compounds of formula (I) wherein A, E G, J, L, M, R1, R2, and R3 are as defined in the specification and claims. The invention also relates to pharmaceutical compositions containing such compounds and methods for preparing the compounds and compositions. The compounds are metabotropic glutamate receptor antagonists and are useful for the treatment of a variety of CNS disorders.
申请公布号 US8093263(B2) 申请公布日期 2012.01.10
申请号 US20090348962 申请日期 2009.01.06
申请人 GATTI MCARTHUR SILVIA;GOETSCHI ERWIN;WICHMANN JUERGEN;WOLTERING THOMAS JOHANNES;HOFFMANN-LA ROCHE INC. 发明人 GATTI MCARTHUR SILVIA;GOETSCHI ERWIN;WICHMANN JUERGEN;WOLTERING THOMAS JOHANNES
分类号 C07D471/04;A61K31/437;A61K31/519;A61P25/16;A61P25/18;A61P25/28 主分类号 C07D471/04
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