摘要 |
The present invention provides a method for producing a medical device, preferably an ophthalmic device, more preferably a contact lens, made of a stabilized poly(oxyalkylene)containing polymeric material. The method of the invention comprises the steps of: curing, in a mold, a composition comprising (a) a prepolymer having at least one poly(oxyalkylene) unit, (b) a biocompatible organic multi-acid or biocompatible salt thereof in an amount sufficient to improve the stability of the poly(oxyalkylene)-containing polymer made from the composition, (c) optionally a photoinitiator or a thermal initiator, and (d) optionally one or more vinylic monomers, to form the medical device being less susceptible to oxidative degradation; and removing the medical device from the mold. |
申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH;DEVLIN, BRIAN, GERRARD;MEDINA, ARTURO, NORBERTO;SENTELL, KAREN, BELINDA;PERREAULT, STEPHEN, RAYMOND;TENA, MIREILLE |
发明人 |
DEVLIN, BRIAN, GERRARD;MEDINA, ARTURO, NORBERTO;SENTELL, KAREN, BELINDA;PERREAULT, STEPHEN, RAYMOND;TENA, MIREILLE |