发明名称 |
Substituted tetracycline compounds for the treatment of malaria |
摘要 |
This invention provides a method for treating or preventing malaria in a subject. The method includes administering to the subject an effective amount of a substituted tetracycline compound, such that malaria is treated or prevented. In one aspect, the invention relates to pharmaceutical compositions which include an effective amount of a tetracycline compound to treat malaria in a subject and a pharmaceutically acceptable carrier. The substituted tetracycline compounds of the invention can be used to in combination with one or more anti-malarial compounds or can be used to treat or prevent malaria which is resistant to one or more other anti-malarial compounds. |
申请公布号 |
US8088820(B2) |
申请公布日期 |
2012.01.03 |
申请号 |
US20030692563 |
申请日期 |
2003.10.24 |
申请人 |
DRAPER MICHAEL;NELSON MARK L.;PARATEK PHARMACEUTICALS, INC. |
发明人 |
DRAPER MICHAEL;NELSON MARK L. |
分类号 |
A61K31/36;A61K31/353;A61K31/385;A61K31/473;A61K31/65;C07D317/50;C07D317/54;C07D317/58 |
主分类号 |
A61K31/36 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|