发明名称 METHOD FOR PURIFYING PROTEIN USING AMINO ACID
摘要 For purifying a protein such as an antibody on a large scale, there has been required a method which is economically advantageous and enables purification to high purity. Disclosed is a method for purifying a protein through at least one chromatography step, wherein a buffer solution (for example, an equilibrated buffer solution, a buffer solution for washing and/or a buffer solution for elution) to be used in at least one chromatography step contains an amino acid or a dipeptide, oligopeptide or polyamino acid of the same so that the protein can be purified to a high purity with an extremely small content of impurities (for example, polymers and host cell proteins).
申请公布号 WO2011162210(A1) 申请公布日期 2011.12.29
申请号 WO2011JP64074 申请日期 2011.06.20
申请人 KYOWA HAKKO KIRIN CO., LTD.;ISHIHARA TAKASHI 发明人 ISHIHARA TAKASHI
分类号 C07K1/36;C07K1/16;C07K1/18;C07K1/20;C07K1/22;C07K16/00 主分类号 C07K1/36
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