HIGHLY SPECIFIC ANTIBODIES, COMPOSITION AND METHODS THEREOF
摘要
<p>The present disclosure relates to phosphorylation of NPM1 by Aurora kinases A and B at a single residue, serine 125 during mitosis. In order to detect the phosphorylated-S125- NPM1 in the cells, highly specific antibodies were generated against it. Hence the present disclosure also relates to highly specific antibodies to detect Aurora kinases A and B phosphorylation at Ser125-NPM1 and its uses thereof.</p>
申请公布号
WO2011161630(A1)
申请公布日期
2011.12.29
申请号
WO2011IB52734
申请日期
2011.06.22
申请人
JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH;KUNDU, TAPAS KUMAR;SHANDILYA, JAYASHA;SENAPATI, PARIJAT