发明名称 |
MICROFLUIDIC DEVICES FOR MEASUREMENT OR DETECTION INVOLVING CELLS OR BIOMOLECULES |
摘要 |
Embodiments of the invention are related to microfluidic devices for detecting or determining the concentration of biomolecules in an analyte comprising: a channel, wherein a surface of said channel is fabricated to be functionalized with at least one molecule selected to interact with a biomolecule, said channel being configured to interact with a microsphere, wherein a surface of said microsphere is fabricated to be functionalized with at least one same or different molecule selected to interact with said biomolecule; a second channel in fluid communication with said first channel; a system to move fluid containing said microsphere through said first and second channels; and a system to measure a change in electrical impedance or optical microscopy across said second channel as said microsphere moves through said second channel. Other embodiments concern related devices, and methods of making and using. |
申请公布号 |
US2011312518(A1) |
申请公布日期 |
2011.12.22 |
申请号 |
US201113070002 |
申请日期 |
2011.03.23 |
申请人 |
DAVIS RONALD W.;JAVANMARD MEHDI;MINDRINOS MICHAEL N.;MOK JANINE A.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
DAVIS RONALD W.;JAVANMARD MEHDI;MINDRINOS MICHAEL N.;MOK JANINE A. |
分类号 |
C40B30/04;C12M1/34;C40B60/12;G01N21/17;G01N27/02 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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