发明名称 COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES
摘要 The present invention provides compounds of Formula (I), compositions comprising an effective amount of a compound of Formula (I), optionally with chemotherapeutic drugs such as a tubulin-binding drug, and methods of their use for reducing the toxicity of cytotoxic agents, treating or preventing cancer or a neuropathic disorder, inducing a chemoprotective phase II enzyme, DNA, or protein synthesis, enhancing the immune system, treating inflammation, improving and enhancing general health or well-being, and methods for making compounds of Formula (I).
申请公布号 US2011312904(A1) 申请公布日期 2011.12.22
申请号 US200913061508 申请日期 2009.08.27
申请人 SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 DANISHEFSKY SAMUEL J.;CHOU TING-CHAO;LEI XIAOGUANG;YUN HEEDONG;NG FAY;HARTUNG JOHN;SAMES DALIBOR
分类号 A61K31/7048;A61K31/047;A61K31/075;A61K31/165;A61K31/196;A61K31/337;A61K31/343;A61K31/357;A61K31/4192;A61K31/427;A61K31/661;A61K31/675;A61P3/00;A61P25/08;A61P25/16;A61P25/18;A61P25/28;A61P29/00;A61P35/00;A61P35/02;A61P39/02;C07C33/04;C07C33/30;C07C43/315;C07D317/20;C07D317/24;C07D317/26;C07D403/04;C07D405/06;C12N5/071 主分类号 A61K31/7048
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