METHOD FOR PREDICTING A THERAPY RESPONSE IN SUBJECTS WITH MULTIPLE SCLEROSIS
摘要
<p>A method is provided for determining the efficacy of interferon -beta (IFN-ß) therapy in a subject with multiple sclerosis. One step of the method can include obtaining a biological sample from the subject. After obtaining the biological sample, the expression level of at least one interferon-regulated gene (IRG) and/or variant thereof can be determined. Increased or decreased expression of the at least one IRG and/or variant thereof as compared to a control may indicate that the subject will respond poorly to IFN-ß therapy.</p>
申请公布号
WO2011159970(A2)
申请公布日期
2011.12.22
申请号
WO2011US40810
申请日期
2011.06.17
申请人
THE CLEVELAND CLINIC FOUNDATION;RUDICK, RICHARD, A.;RANSOHOFF, RICHARD, M.