HAND HELD MICRO PCR DEVICE

摘要

A hand held micro PCR device comprises a) a low temperature co-fired ceramic (LTCC) micro PCR chip comprising a heater, a reaction chamber to load a sample, b) a heater control to regulate the heater on basis of input received from a temperature sensor, c) an optical detection system to detect a fluorescence signal from the sample, and d) at least one communication interface to interact with other device(s). The other device is selected from group comprising smart phone, PDA and programmable device which collects temperature of the chip and the amplified signal from the hand held device. The temperature sensor can be placed outside the chip or embedded in at least one layer of the chip to measure temperature of the chip. The optical detection system can comprises a light source and a photo detector and the optical detection system is selected from the group comprising of a beamsplitter optical detection system, a hybrid optical detection system and bifurcated optical detection system.