发明名称 |
NMN MODULATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS |
摘要 |
The invention relates to a nicotinamide mononucleotide (NMN) modulator useful as a neuroprotective medicament in the treatment of neurodegenerative disorders, in particular but not exclusively disorders involving axon degeneration of neuronal tissue such as Wallerian degeneration, to the use of NMN as a biomarker for axon degeneration, to a method of demonstrating axon degeneration using an NMN-based biomarker, to a diagnostic kit for detecting axon degeneration, to a method of screening for an NMN modulator, and to an NMN modulator identified using the aforementioned screening method. |
申请公布号 |
WO2011135332(A3) |
申请公布日期 |
2011.12.22 |
申请号 |
WO2011GB50770 |
申请日期 |
2011.04.19 |
申请人 |
BABRAHAM INSTITUTE;COLEMAN, MICHAEL;CONFORTI, LAURA |
发明人 |
COLEMAN, MICHAEL;CONFORTI, LAURA |
分类号 |
A61K31/4409;A61K31/445;A61P25/28 |
主分类号 |
A61K31/4409 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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