USE OF B-TYPE BOTULINUS TOXIN FOLLOWED BY A-TYPE BOTULINUS TOXIN FOR TREATING DYSTONIA

摘要

PROBLEM TO BE SOLVED: To provide a method for obtaining a treatment effect even after clinical response for administration of an A-type botulinus toxin has decreased in treatment of neuromuscular disease.

SOLUTION: An effective treatment amount of the A-type botulinus toxin is administrated until a patient experiences a decrease in clinical response for its administration, and thereafter an effective treatment amount of a B-type botulinus toxin is administrated to the patient so that neuromuscular disease is treated.

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