发明名称 |
Anti-IL-3Ralpha antibody for use in treatment of blood tumor |
摘要 |
Disclosed are: an antibody against a human IL-3Rα chain, which does not inhibit an IL-3 signal, can bind to a B domain of the human IL-3Rα chain, and cannot bind to a C domain of the human IL-3Rα chain; a composition for preventing or treating a blood tumor in which IL-3Rα-expressing cells are observed in a bone marrow or a peripheral blood in a subject, which is characterized by comprising the human IL-3Rα antibody as an active ingredient; and a method for treating a blood tumor in which IL-3Rα-expressing cells are observed in a bone marrow or a peripheral blood, which is characterized by administering a composition containing the human IL-3Rα antibody as an active ingredient to a subject. |
申请公布号 |
AU2010242598(A1) |
申请公布日期 |
2011.12.15 |
申请号 |
AU20100242598 |
申请日期 |
2010.04.27 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
TAWARA, TOMONORI;TAKAYANAGI, SHINICHIRO;INAGAKI, YOSHIMASA |
分类号 |
C07K16/28;A61K39/395;A61P35/02;C07K16/46;C12N15/02;C12N15/09;C12P21/08;C12R1/91;G01N33/53;G01N33/574;G01N33/577 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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