| 摘要 |
<P>PROBLEM TO BE SOLVED: To evaluate and possibly exclude from treatment patients eligible for treatment with iNO, who have pre-existing left ventricular dysfunction (LVD). <P>SOLUTION: A method of treating a term and near-term neonate having hypoxic respiratory failure associated with a clinical or echocardiographic evidence of pulmonary hypertension includes: (a) providing pharmaceutically acceptable nitric oxide gas to a medical provider; and (b) informing the medical provider that excluding the patients who have pre-existing LVD from the treatment reduces the risk or prevents the occurrence of the adverse event or serious adverse event associated with a medical treatment. The left ventricular afterload may be minimized or reduced by administering a pharmaceutical dosage form comprising nitroglycerin or calcium channel blocker to the patient. The left ventricular afterload may also be minimized or reduced using an intra-aortic balloon pump. <P>COPYRIGHT: (C)2012,JPO&INPIT |
