PURIFIED COMPOSITIONS OF CARDIOVASCULAR PROGENITOR CELLS

摘要

Composition and methods are provided for the prospective enrichment of human cardiovascular progenitor cells, which can be differentiated into cardiomyocytes, from in vitro cultures of stem cells. The stem cells are cultured in conditions permissive for differentiation into cardiovascular progenitor cells, and cardiovascular progenitor cells are sorted for expression of one or more of the markers ROR2, CD13, KDR and PDGF R, where the progenitor cells positively express these markers. Highly enriched populations of cardiomyocyte lineage cells can be obtained.