SINGLE NUCLEOTIDE POLYRMORPHISMS IMPLICATED IN BREAST CANCER AND USE THEREOF

摘要

PURPOSE: A breast cancer-associated SNP is provided to be used in an in vitro diagnosis system with simplicity and high reliability. CONSTITUTION: A kit for breast cancer diagnosis contains a primer or probe which specifically binds to 10-100 serial nucleotide sequences, containing SNP site(GenBank SNP database, rs 2972388) having T at 401th nucleotide of sequence number 1. A T allele is TT homozygote. The kit is applied to Asians. A method for detecting a marker for breast cancer comprises a step of detecting the SNP as a CDK7 gene SNP. The detection is performed by a microarray method or gene amplification method.