发明名称 TREATMENT OF METHIONINE SULFOXIDE REDUCTASE A (MSRA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO MSRA
摘要 The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Methionine Sulfoxide Reductase A (MSRA), in particular, by targeting natural antisense polynucleotides of Methionine Sulfoxide Reductase A (MSRA). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of MSRA.
申请公布号 WO2011150007(A2) 申请公布日期 2011.12.01
申请号 WO2011US37835 申请日期 2011.05.25
申请人 OPKO CURNA LLC;COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA 发明人 COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA
分类号 C12N15/113;A61K31/7088;A61K48/00;C12N15/53;C12N15/63 主分类号 C12N15/113
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