| 摘要 |
PURPOSE: An FPR2 liang having palmitic acid conjugated to peptide sequence of intracellular loop 3 is provided to effectively enhance immune response of leukocytes. CONSTITUTION: An FPR2 ligand is prepared by binding palmitic acid to a peptide sequence of intracellular loop 3 of formyl peptide receptor 2. The peptide sequence is KIHKKGMIKSSRPLRV. A pharmaceutical composition for treating tumor, infection, and inflammatory diseases contains the ligand as an active ingredient. The pharmaceutical composition further contains sterile water, saline solution, dextrose, glycerol, ethanol, emulsifier, suspension, surfactant, stabilizing agent, excipient, preservative, or binder.
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