Apparatus and methods for packing chromatography columns

摘要

A chromatographic apparatus may include a hydraulic lifting mechanism axially movable from a lowered position to a raised position such that a column and flange of the apparatus are axially movable with the hydraulic lifting mechanism. In a packing system, a mobile column module may be moved into engagement with a packing station by engaging a flange of the column module with a fixture of the packing station. After packing a column of the column module, the column module may be removed from the packing station with a piston head locked in the column to maintain packing pressure. The packing station may be utilized to unpack the column. A hydraulic lifting mechanism may be operated to lower one or more portions of the column module such that the one or more portions may be separately removed from the packing system.